Clinical Diagnosis
Our droplet digital PCR (ddPCR) system is offering clinical diagnostics by delivering results in just 3 hours (TAT) with remarkable precision and absolute nucleic acid quantification. This advanced technology makes highly sensitive and reliable applications across multiple critical scenario of patient care.
Key Clinical Applications
Infectious Disease Diagnosis:
The system provides ultra-sensitive diagnosis and precise bacterial load, counting for pathogens like HIV, HBV, and CMV. Its capability of detection of low-abundance targets is important to do early diagnosis, and manage antimicrobial resistance.
Oncology & Liquid Biopsy:
About cancer management, the ddPCR system is proficient in liquid biopsy. It enables the non-invasive detection and monitoring of ctDNA, identifying key genetic mutations, copy number variations with high accuracy to inform treatment decisions.
Genetic Disease Screening:
The technology offers excellent solutions for Genetic Disease Screening. It ensures highly accurate detection of copy number variations, single-gene disorders, and chromosomal aneuploidies, supporting carrier screening, prenatal diagnosis, and newborn screening programs.
Biopharmaceutical R&D
Gene Editing Efficiency Validation
The ddPCR system enables absolute quantification of editing efficiency, precisely determining the frequency of gene knock-outs, knock-ins, or point mutations in CRISPR/Cas9 and other gene editing technologies. By detecting low-abundance editing events, the system effectively values off-target effects, providing essential quality control data for preclinical studies in gene and cell therapies. This accelerates the development of effective therapeutic approaches.
Antibody Drug & Vaccine R&D
In biopharmaceutical development, ddPCR offers highly sensitive analytical support for antibody drugs and vaccine research:
Stability & Expression Monitoring:
Precisely monitors copy number variations and expression stability of target genes in cell lines, optimizing stable cell line screening.
Viral Vector Titer Determination:
Provides absolute quantification of viral genomes used in vaccines or gene therapy vectors, ensuring product consistency and potency.
Host Cell Residual DNA Detection:
Makes high-sensitivity quantification of trace residual host DNA during production, meeting stringent quality control standards for regulatory compliance.
Agricultural and Food Testing
Genetically Modified (GM) Crop Detection
Food and Animal/Plant Disease Surveillance
Environmental Surveillance
Water Quality & Pathogen Monitoring
Drinking water safety:
Detection of low-abundance pathogens (Legionella, Cryptosporidium, norovirus)
Wastewater surveillance:
Monitoring of enteric viruses and antibiotic resistance genes
Recreational water safety:
Rapid assessment of fecal indicator bacteria (E. coli, enterococci)
Early warning systems:
Sensitive detection of harmful algal bloom organisms
Environmental DNA (eDNA) Analysis
The system revolutionizes biodiversity monitoring through non-invasive species detection:
Endangered species tracking:
Ultrasensitive detection from water, soil, or air samples
Invasive species monitoring:
Early detection of non-native organisms in ecosystems
Biodiversity assessment:
Comprehensive community analysis from environmental samples
Bioremediation monitoring:
Tracking specific microbial consortia in contaminated sites
Forensic Science
Human Identification & DNA Profiling
Low-template DNA analysis:
Reliable profiling from touch DNA, single cells, or degraded samples
Mixture deconvolution:
Separation and quantification of multiple contributors in complex samples
Y-chromosome & mitochondrial DNA analysis:
Separation and quantification of multiple contributors in complex samples
Rapid disaster victim identification:
High-throughput processing for mass casualty incidents
Body Fluid Identification & Biomarker Detection
The system provides simultaneous detection of multiple forensic markers:
Tissue-specific mRNA profiling:
Identification of blood, semen, saliva, vaginal secretions, and skin cells
Microbiome analysis:
Geographic and individual-specific microbial signatures
Epigenetic marker detection:
Age estimation and tissue origin determination
Externally visible characteristics:
Predictive markers for hair, eye, and skin pigmentation
Despite the numerous valuable capabilities of droplet digital PCR (ddPCR), each manufacturer typically focuses its R&D efforts on developing kits for just one or a few of these functions.
While the vast majority of manufacturers are contributing to the research market, our primary focus and R&D direction are centered on clinical application and diagnosis, dedicated to advancing the accuracy of sepsis diagnostic outcomes.
As one of the leading potential solution manufacturers and suppliers in China, we offer a wide range of products with superior quality. Please feel free to wholesale custom made potential solution from our factory. Contact us for more details.
